Web1 Oct 2024 · Like many other ubiquitin family proteins, Ufm1 is translated as a precursor, the C-terminal dipeptide of which must be cleaved to yield mature Ufm1, which is … Ubiquitin-fold modifier 1, also known as UFM1, is a protein which in humans is encoded by the UFM1 gene. UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 and E2-like conjugating enzyme UFC1. This process is often referred to as UFMylation. See more UFM1 shares several common properties with ubiquitin (Ub) and the other ubiquitin-like proteins (UBLs). Ufm1 has similar tertiary structure to Ub but lacks any obvious sequence similarity. It is synthesized as an … See more • Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells" See more • Overview of all the structural information available in the PDB for UniProt: P61960 (Human Ubiquitin-fold modifier 1) at the PDBe-KB. See more
Nontraditional translation is the key to UFMylation and beyond
Web21 Oct 2024 · 具体而言,二甲双胍通过抑制其 UFMylation 过程来降低 SLC7A11 的蛋白质稳定性。此外,二甲双胍与柳氮磺吡啶系统 xc-抑制剂联合使用可以协同作用诱导铁死亡并 … Web3 Dec 2024 · DDRGK1作为Ufmylation修饰的两个底物之一,还是Ufmylation修饰系统所必需的组分,参与其他底物的修饰调控。然而,其具体的生物学功能还知之甚在本次研究中, … cgs medicare ptan lookup
Emerging role of UFMylation in secretory cells involved in the ...
Web20 Aug 2024 · UFMylation修饰是最新被鉴定的一种类泛素化修饰,与泛素化修饰类似,UFM1以前体形式被合成,经过UfSP1或UfSP2剪切,形成活化的UFM1-G83后被一个特 … http://cjbmb.bjmu.edu.cn/CN/Y2024/V35/I3/229 WebNational Center for Biotechnology Information cgs medicare provider forms