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WebHaving chronic kidney disease changes your need for some nutrients. Some of the reasons are: The waste products that build up in your body each day can change the way your body uses vitamins and minerals. Some of the medicines you take can change the way your body uses certain vitamins and minerals. WebJul 10, 2024 · The abnormal expression of type IV collagen causes loss of GBM integrity, abnormal leakage of proteins through the GBM, and excessive reabsorption of protein in the proximal tubules of the kidney. WebAug 17, 1998 · People with high blood pressure have elevated blood levels of collagen, a protein, which may help explain why these individuals are at risk for heart failure as well as kidney and other organ ... eragon second book